Dose & concentration

Mass, volume, and potency conversions with documented assumptions.

Summary

This calculator uses standard concentration definitions (mass/volume) and assay-based potency adjustments commonly documented in GMP batch records. Calculations align with documentation expectations in ICH Q7. Confirm formulas with your site SOPs.

Use any two of mass, volume, and concentration to compute the third value. For potency adjustments, use the assay percentage to convert between target active mass and the material to weigh.

Maintain consistent units throughout calculations and record the assumptions used for each conversion.

Step-by-step: Convert mass, volume, and potency

Confirm units and specification context
Use consistent units for mass and volume and document any conversions before calculation.
Provide two known values
Enter any two of mass, volume, or concentration to compute the third value.
Apply potency adjustments if needed
Use the assay percentage to calculate material to weigh or the active mass delivered.

Concentration inputs

Mass mg

Volume mL

Concentration mg/mL

Enter any two values to compute the third.

Mass / volume conversions

Concentration =Mass (mg)Volume (mL)

Mass (mg) =Concentration (mg/mL)1* Volume (mL)

Volume (mL) =Mass (mg)Concentration (mg/mL)

Provide any two values to calculate the third.

Potency adjustment

Potency %

Target active mass mg

Material mass mg

Provide potency and one mass value to compute the other.

Potency-adjusted results

Material mass =Target active massPotency fraction

Active mass =Material mass1* Potency fraction

Provide potency and a mass value to calculate the other.

Regulatory references

Read-only guidance aligned with major regulatory bodies.

FDAEMAICHUSPISPEPDA